Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74042 | 0.77 | — | — | |
| SCHEMBL5393690 | 0.77 | — | — | |
| SCHEMBL9957766 | 0.75 | — | — | |
| SCHEMBL15256432 | 0.71 | NOS1 (0.33) | — | |
| SCHEMBL17030129 | 0.71 | NOS1 (0.33) | — | |
| SCHEMBL5950548 | 0.69 | — | — | |
| SCHEMBL3079040 | 0.69 | CYP1A2 (0.48) | MEN1CYP1A2KMT2ASMN1; SMN2TSHR | |
| SCHEMBL23327585 | 0.69 | — | — | |
| SCHEMBL17030070 | 0.69 | NOS1 (0.32) | — | |
| SCHEMBL12629147 | 0.69 | NOS1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063819-A | PROTECTING NEURONS FROM DAMAGE BY ADMINISTERING TO HUMANS POLYGUADINO COMPOUNDS | CYPROS PHARMACEUTICAL CORP. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1998036743-A1 | NEUROPROTECTIVE POLY-GUANIDINO COMPOUNDS WHICH BLOCK PRESYNAPTIC N AND P/Q CALCIUM CHANNELS | CYPROS PHARMACEUTICAL CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |