Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.57 |
| ▸ | CTSK | P43235 | 14/20 | 0.57 |
| ▸ | CTSS | P25774 | 11/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447217 | 0.88 | CTSL (0.72) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL7449108 | 0.87 | CTSL (0.54) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7473433 | 0.85 | CTSL (0.79) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7462958 | 0.82 | CTSL (0.59) | CTSLCTSKCTSS | |
| SCHEMBL7451447 | 0.82 | CTSL (0.64) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL7451990 | 0.81 | CTSL (0.61) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL7506810 | 0.80 | CTSL (0.61) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL8158075 | 0.80 | CTSL (0.61) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL7480570 | 0.79 | CTSL (0.57) | CTSLCTSKCTSSCTSBITGB3 | |
| SCHEMBL7452213 | 0.79 | CTSL (0.57) | CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | disclosed |
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |