Benzene

Benzene

SCHEMBL7448458

CC(C)(C)OC(C)(C)C.c1ccccc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.33
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL20917732 0.86 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL28365346 0.85 ALDH1A1 (0.46) ALDH1A1TSHRTDP1
SCHEMBL8913 0.85
Biphenyl SCHEMBL1193167 0.80 ALDH1A1 (0.53) ALDH1A1TSHRTDP1MAPK1ALOX15
Pyridine SCHEMBL7449430 0.80 TSHR (0.53) TSHRTDP1
Ethane SCHEMBL353672 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL30933076 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Methane SCHEMBL30637 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
SCHEMBL31678023 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1
Water SCHEMBL8067978 0.80 ALDH1A1 (0.42) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436781-B Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2023-03-24 CN claimed
CN-114436781-A Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2022-05-06 CN claimed
CN-114436781-B Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2023-03-24 CN disclosed
CN-114436781-A Preparation method of substituted phenol compound 安徽觅拓材料科技有限公司 2022-05-06 CN disclosed
EP-0977743-A1 PROTEASE INHIBITORS Smithkline Beecham (US) 2000-02-09 EP disclosed
WO-1998049152-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-05 WO disclosed