Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | UMPS | P11172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7507025 | 0.75 | KDM4E (0.47) | LMNAMEN1KMT2APDE4DKDM4E | |
| SCHEMBL15318187 | 0.73 | MAPK1 (0.36) | LMNAMEN1KMT2AHTR6KDM4E | |
| SCHEMBL5337870 | 0.72 | MAPK1 (0.57) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL8597031 | 0.72 | DYRK1A (0.42) | LMNAPDE4DPDPK1L3MBTL1CCNA2 | |
| SCHEMBL6336859 | 0.71 | PDPK1 (0.41) | LMNAPDE4DPDPK1L3MBTL1CCNA2 | |
| SCHEMBL15871865 | 0.71 | UMPS (0.40) | LMNAPDE4DPDPK1L3MBTL1CCNA2 | |
| Hydrochloric Acid SCHEMBL1999396 | 0.71 | KDM4E (0.60) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL459936 | 0.71 | KDM4E (0.37) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6559450 | 0.69 | KDM4E (0.40) | LMNAMEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL3997044 | 0.69 | DPP4 (0.36) | PDPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006104-A1 | PYRAZOLOPYRIMIDINONE ANTIANGINAL AGENTS | PFIZER LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |