SCHEMBL7448671

SCHEMBL7448671

Fc1c(Cl)ccc2[nH]ccc12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 9/20 0.47
DRD4 P21917 2/20 0.39
DRD3 P35462 2/20 0.39
DRD2 P14416 1/20 0.39
AHR P35869 3/20 0.38
F7 P08709 1/20 0.38
LTA4H P09960 1/20 0.38
F3 P13726 1/20 0.38
NR4A2 P43354 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
PARP1 P09874 1/20 0.36
AXL P30530 1/20 0.35
PRKCI P41743 1/20 0.35
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6871032 0.77 PARP1 (0.42) RHEBAHRF7LTA4HF3
SCHEMBL31416308 0.77 RHEB (0.50) RHEBDRD4DRD3DRD2AHR
SCHEMBL830446 0.77 RHEB (0.50) RHEBDRD4DRD3DRD2AHR
SCHEMBL25252534 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR
SCHEMBL30774212 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR
SCHEMBL1075774 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR
SCHEMBL8959626 0.74 TNF (0.48) RHEBAHRF7LTA4HF3
SCHEMBL2985458 0.74 AHR (0.38) RHEBAHRPARP1GPR84
SCHEMBL31431597 0.74 AHR (0.38) RHEBAHRPARP1GPR84
SCHEMBL1565897 0.74 AHR (0.52) RHEBAHRNR4A2PARP1PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650345-A1 HETEROCYCLIC COMPOUND AND USE THEREOF IN MEDICINE Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) 2025-11-19 EP disclosed
WO-2025235362-A1 INDOLINONE COMPOUNDS AS KCa3.1 POTASSIUM CHANNEL BLOCKERS D. E. SHAW RESEARCH, LLC (US) 2025-11-13 WO disclosed
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2025-03-06 US disclosed
EP-4464693-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT Daewoong Pharmaceutical Co., Ltd. (KR) 2024-11-20 EP disclosed
WO-2024201248-A1 COMPOUNDS AND METHODS FOR DEGRADING GSPT1 PIN THERAPEUTICS, INC. (KR) 2024-10-03 WO disclosed
CN-118632836-A Novel aminobenzene derivative having cancer cell growth inhibitory effect and preventive or therapeutic pharmaceutical composition containing the same as active ingredient 株式会社大熊制药 2024-09-10 CN disclosed
WO-2023136645-A1 NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT 주식회사 대웅제약 2023-07-20 WO disclosed
WO-2023130070-A2 CARBOLINE COMPOUNDS AND USE THEREOF PTC THERAPEUTICS, INC. (US) 2023-07-06 WO disclosed
US-20230127839-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-04-27 US disclosed
US-20230127839-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-04-27 US disclosed
WO-2022015957-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2022-01-20 WO disclosed
WO-2021138434-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2021-07-08 WO disclosed
EP-0983264-A1 METHOD OF MANUFACTURING SERTINDOLE H. LUNDBECK A/S (DK) 2000-03-08 EP disclosed
WO-1998051685-A1 METHOD OF MANUFACTURING SERTINDOLE H. LUNDBECK A/S (DK) 1998-11-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127839-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 RHEB 1004/4885DRD4 4714/4885DRD3 4705/4885
US-20250074889-A1 Novel Aminobenzene Derivative Having Cancer Cell Growth Inhibitory Effect, and Preventive or Therapeutic Pharmaceutical Composition Containing Same as Active Ingredient MKI67, CCNB1, ALDH7A1 RHEB 929/4885DRD4 3764/4885DRD3 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.