SCHEMBL25252534

SCHEMBL25252534

Oc1c(Cl)ccc2[nH]ccc12

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 9/20 0.47
DPP4 P27487 1/20 0.39
DRD4 P21917 2/20 0.39
DRD3 P35462 2/20 0.39
DRD2 P14416 1/20 0.39
AHR P35869 2/20 0.38
F7 P08709 1/20 0.38
LTA4H P09960 1/20 0.38
F3 P13726 1/20 0.38
NR4A2 P43354 1/20 0.38
TYR P14679 1/20 0.38
USP2 O75604 1/20 0.38
GAA P10253 1/20 0.38
ALOX15 P16050 1/20 0.38
RAD51 Q06609 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAOB P27338 1/20 0.37
PARP1 P09874 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31416308 0.77 RHEB (0.50) RHEBDRD4DRD3DRD2AHR
SCHEMBL830446 0.77 RHEB (0.50) RHEBDRD4DRD3DRD2AHR
SCHEMBL1876842 0.77 TYR (0.40) RHEBAHRTYRUSP2GAA
SCHEMBL3248883 0.74 TYR (0.38) RHEBAHRTYRUSP2GAA
SCHEMBL7448671 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR
SCHEMBL30774212 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR
SCHEMBL8252615 0.74 TYR (0.38) RHEBAHRTYRUSP2GAA
SCHEMBL2503153 0.74 RHEB (0.40) RHEBAHRF7LTA4HF3
SCHEMBL29415607 0.74 TYR (0.38) RHEBAHRTYRUSP2GAA
SCHEMBL1075774 0.74 RHEB (0.47) RHEBDRD4DRD3DRD2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057861-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-02-20 US disclosed
US-12138276-B2 Halogenated psilocybin derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2024-11-12 US disclosed
US-20240299427-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2024-09-12 US disclosed
US-11998557-B2 Halogenated psilocybin derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2024-06-04 US disclosed
US-20230293558-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-09-21 US disclosed
EP-4208445-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-07-12 EP disclosed
CN-116348106-A Halogenated nupharicin derivatives and methods of use 恩维瑞克生物科学加拿大公司 2023-06-27 CN disclosed
WO-2022047579-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12138276-B2 Halogenated psilocybin derivatives and methods of using CES2, MAOB, CNR1 RHEB 2164/4885DPP4 4014/4885DRD4 137/4885
US-20240299427-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING CES2, MAOB, CNR1 RHEB 2164/4885DPP4 4014/4885DRD4 137/4885
US-20230293558-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING CES2, MAOB, CNR1 RHEB 2164/4885DPP4 4014/4885DRD4 137/4885
US-11998557-B2 Halogenated psilocybin derivatives and methods of using CES2, MAOB, CNR1 RHEB 2164/4885DPP4 4014/4885DRD4 137/4885
US-20250057861-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING CES2, MAOB, CNR1 RHEB 2164/4885DPP4 4014/4885DRD4 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.