Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7405743 | 0.98 | NAMPT (0.44) | NAMPTELANECA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3817699 | 0.83 | MDM2 (0.42) | LMNAKMT2AMEN1MAPK1BCHE | |
| Hydrochloric Acid SCHEMBL9474612 | 0.83 | MDM2 (0.42) | LMNAKMT2AMEN1MAPK1BCHE | |
| Hydrochloric Acid SCHEMBL9474603 | 0.83 | MDM2 (0.42) | LMNAKMT2AMEN1MAPK1BCHE | |
| SCHEMBL6026706 | 0.83 | ELANE (0.53) | ELANECA12CA1CA2CA9 | |
| SCHEMBL8031605 | 0.83 | ELANE (0.53) | ELANECA12CA1CA2CA9 | |
| SCHEMBL655368 | 0.83 | ELANE (0.53) | ELANECA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL1171032 | 0.81 | ELANE (0.52) | ELANECA12CA1CA2CA9 | |
| SCHEMBL6555717 | 0.80 | CA12 (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7373973 | 0.80 | MAPT (0.55) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047599-A1 | SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-18 | — | — | WO | disclosed |