Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448807 | 1.00 | IDO1 (0.49) | IDO1PAMHTR2APPARAPPARD | |
| SCHEMBL3034599 | 0.76 | IDO1 (0.52) | IDO1PAMHTR2APPARAPPARD | |
| SCHEMBL27430134 | 0.75 | IDO1 (0.41) | IDO1PAMPPARAPPARDPPARG | |
| SCHEMBL28281032 | 0.73 | IDO1 (0.49) | IDO1PAMHTR2A | |
| SCHEMBL8741139 | 0.73 | IDO1 (0.57) | IDO1PAMHTR2APPARAPPARD | |
| SCHEMBL30967195 | 0.73 | IDO1 (0.57) | IDO1PAMHTR2APPARAPPARD | |
| SCHEMBL7989832 | 0.73 | ALOX5 (0.44) | IDO1HTR2APPARAPPARDPPARG | |
| SCHEMBL7989829 | 0.73 | ALOX5 (0.44) | IDO1HTR2APPARAPPARDPPARG | |
| SCHEMBL13641776 | 0.73 | IDO1 (0.57) | IDO1PAMHTR2APPARAPPARD | |
| SCHEMBL27905912 | 0.71 | IDO1 (0.46) | IDO1PAMPPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |