Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453420 | 0.91 | PDE10A (0.60) | PDE10AFLT4 | |
| SCHEMBL15048494 | 0.81 | PDE10A (0.55) | PDE10A | |
| SCHEMBL7457191 | 0.79 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2161270 | 0.79 | PDE10A (0.58) | PDE10A | |
| SCHEMBL7448971 | 0.77 | PDE10A (0.49) | PDE10A | |
| SCHEMBL7453820 | 0.75 | PDE10A (0.51) | PDE10A | |
| SCHEMBL7453331 | 0.74 | PDE10A (0.58) | PDE10A | |
| SCHEMBL7449198 | 0.73 | PDE10A (0.59) | PDE10A | |
| SCHEMBL7449158 | 0.73 | TSHR (0.34) | PDE10A | |
| SCHEMBL7455525 | 0.72 | PDE10A (0.61) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580207-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2013-04-17 | — | — | EP | claimed |
| WO-2011154327-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | WO | claimed |
| EP-2580207-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011154327-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | WO | disclosed |