Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449102 | 0.94 | PTGER1 (0.46) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7449236 | 0.88 | PTGER1 (0.46) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7505365 | 0.86 | PTGER1 (0.41) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7449277 | 0.82 | PTGER1 (0.47) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7607568 | 0.81 | PTGER1 (0.53) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7446264 | 0.81 | TLR7 (0.50) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7512520 | 0.80 | PTGER1 (0.42) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7513283 | 0.80 | SMN1; SMN2 (0.50) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7442407 | 0.79 | PTGER1 (0.43) | PTGER1TLR7PTGER4PTGER3PTGER2 | |
| SCHEMBL7448062 | 0.79 | TLR7 (0.48) | PTGER1TLR7SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |