Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophanate SCHEMBL29398343 | 0.98 | ALDH1A1 (0.70) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| Thiophanate SCHEMBL20842 | 0.98 | ALDH1A1 (0.70) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL12336304 | 0.94 | ALDH1A1 (0.64) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| Thiophanate SCHEMBL10922494 | 0.94 | ALDH1A1 (0.79) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11694452 | 0.94 | ALDH1A1 (0.79) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11835690 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11793473 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11834021 | 0.92 | ALDH1A1 (0.71) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11837150 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HPGDLMNAALOX15HSD17B10 | |
| SCHEMBL11821411 | 0.91 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109909-A2 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC. (CA) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014236-A2 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC. (CA) | 2000-03-16 | — | — | WO | disclosed |