Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148479 | 0.88 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL7403138 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL14304939 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL18147563 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL18147565 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL11335712 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL15486247 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL11342103 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL30379309 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1POLBTDP1 | |
| SCHEMBL19878308 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801170-A | Heterocyclic biphenylylamides useful as 5HT1D antagonists | SMITHKLINE BEECHAM PLC (GB) | 1998-09-01 | — | — | US | disclosed |
| EP-0733048-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015954-A1 | HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-06-15 | — | — | WO | disclosed |