SCHEMBL744967

SCHEMBL744967

O=C(c1ccc(F)c(C(=O)C(O)c2ccccc2)c1)c1ccc(N(CC2CC2)c2ccc(Cl)cc2)cn1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTC4S Q16873 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14676117 0.88 LTC4S (0.79) LTC4S
SCHEMBL14675572 0.88 LTC4S (0.82) LTC4S
SCHEMBL14676760 0.86 LTC4S (0.79) LTC4S
SCHEMBL744966 0.86 LTC4S (0.61) LTC4S
SCHEMBL14676419 0.85 LTC4S (0.81) LTC4S
SCHEMBL14675381 0.82 LTC4S (0.81) LTC4S
SCHEMBL236206 0.82 LTC4S (0.69) LTC4S
SCHEMBL239462 0.80 LTC4S (0.67) LTC4S
SCHEMBL238376 0.80 LTC4S (0.66) LTC4S
SCHEMBL14676115 0.79 LTC4S (0.75) LTC4S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2429994-A1 BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS Biolipox AB (SE) 2012-03-21 EP disclosed
WO-2010103283-A1 BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS BIOLIPOX AB (SE) 2010-09-16 WO disclosed