Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988725 | 0.94 | HTT (0.35) | HSP90AA1NR1I2PGRADORA3OPRK1 | |
| SCHEMBL7992894 | 0.88 | HTT (0.41) | HSP90AA1NR1I2PGRADORA3OPRK1 | |
| SCHEMBL7456495 | 0.84 | HTT (0.36) | MEN1KMT2ACHRM3SLC6A4KDM4E | |
| SCHEMBL7507063 | 0.84 | HTT (0.45) | HSP90AA1NR1I2PGRADORA3OPRK1 | |
| SCHEMBL7507530 | 0.80 | HTT (0.39) | MEN1KMT2ACHRM3SLC6A4KDM4E | |
| SCHEMBL7451964 | 0.79 | HTT (0.48) | HSP90AA1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7449725 | 0.77 | TRPA1 (0.37) | NR1I2PGRADORA3OPRK1MEN1 | |
| SCHEMBL7992774 | 0.77 | HTT (0.36) | HSP90AA1NR1I2PGRADORA3OPRK1 | |
| SCHEMBL7448869 | 0.77 | HTT (0.50) | NR1I2PGRADORA3OPRK1KMT2A | |
| SCHEMBL12050573 | 0.77 | MEN1 (0.39) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |