Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 6/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449435 | 0.98 | ITGB3 (0.61) | ITGB3ITGA2BEPHX2HDAC6GLA | |
| Hydrochloric Acid SCHEMBL7450323 | 0.97 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2HDAC6GLA | |
| SCHEMBL7450950 | 0.95 | ITGB3 (0.63) | ITGB3ITGA2BHDAC6GLACYP1A2 | |
| Acetic Acid SCHEMBL7448074 | 0.92 | ITGB3 (0.60) | ITGB3ITGA2BHDAC6CYP1A2FPR2 | |
| SCHEMBL7447038 | 0.92 | ITGB3 (0.72) | ITGB3ITGA2BHDAC6FPR2FPR1 | |
| SCHEMBL7451987 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2HDAC6GLA | |
| Water SCHEMBL7450330 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2HDAC6CYP1A2 | |
| Acetic Acid SCHEMBL7445840 | 0.90 | ITGB3 (0.69) | ITGB3ITGA2BHDAC6FPR2FPR1 | |
| SCHEMBL7444768 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BEPHX2HDAC6CYP1A2 | |
| SCHEMBL7447482 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BEPHX2HDAC6FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |