SCHEMBL7449684

SCHEMBL7449684

NC(=O)c1cc(Cl)ccc1NC(=O)c1sc(CBr)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.52
F2 P00734 4/20 0.51
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6589422 0.86 F10 (0.70) F10F2
SCHEMBL6592797 0.75 F10 (0.71) F10F2
SCHEMBL6593537 0.72 F10 (0.69) F10F2
SCHEMBL6590326 0.72 F10 (0.69) F10F2
SCHEMBL7449776 0.71 F10 (0.58) F10F2
SCHEMBL6589146 0.71 F10 (0.68) F10F2
SCHEMBL6593542 0.70 F10 (0.67) F10F2
SCHEMBL6592947 0.70 F10 (0.62) F10F2
SCHEMBL6590802 0.69 F10 (0.69) F10F2
SCHEMBL6590565 0.69 F10 (0.63) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 2000-10-04 EP disclosed
WO-1999032477-A1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed