Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911540 | 0.79 | — | — | |
| SCHEMBL14021268 | 0.74 | CYP1A2 (0.34) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1415277 | 0.71 | — | — | |
| SCHEMBL22883555 | 0.70 | — | — | |
| SCHEMBL17107802 | 0.69 | CYP1A2 (0.31) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15489317 | 0.67 | CYP1A2 (0.45) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10233612 | 0.65 | CNR1 (0.33) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7449748 | 0.65 | CA1 (0.43) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21205940 | 0.65 | CYP1A2 (0.34) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11033182 | 0.65 | CYP1A2 (0.34) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |