SCHEMBL9911540

SCHEMBL9911540

C#CCCC(=O)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15489317 0.86 CYP1A2 (0.45)
SCHEMBL14021268 0.79 CYP1A2 (0.34)
SCHEMBL7449743 0.79 MAPT (0.34)
SCHEMBL11869077 0.77
SCHEMBL15581683 0.76
SCHEMBL9415087 0.75
SCHEMBL22883555 0.75
SCHEMBL25735749 0.75
SCHEMBL24188384 0.75 QSOX1 (0.34)
SCHEMBL17107802 0.74 CYP1A2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067634-A1 INHIBITORS OF NEF DOWNMODULATION THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-02-29 US disclosed
US-11639364-B2 Potent sialyltransferase inhibitors STICHTING RADBOUD UNIVERSITEIT (NL) 2023-05-02 US disclosed
US-20210107931-A1 New potent sialyltransferase inhibitors STICHTING KATHOLIEKE UNIVERSITEIT (NL) 2021-04-15 US disclosed
US-10697976-B2 Mass labels ELECTROPHORETICS LIMITED (GB) 2020-06-30 US disclosed
US-20170362234-A1 SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2017-12-21 US disclosed
US-20170327542-A9 TEICOPLANIN ANALOGS AND USES THEREOF ACADEMIA SINICA (TW) 2017-11-16 US disclosed
US-20160347795-A1 TEICOPLANIN ANALOGS AND USES THEREOF ACADEMIA SINICA (TW) 2016-12-01 US disclosed
US-20150322087-A1 CEPHALOSPORIN DERIVATIVES AND METHODS OF USE UNIVERSITY OF KANSAS 2015-11-12 US disclosed
US-9139577-B2 Sulfoximine substituted quinazolines for pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-22 US disclosed
US-20150005278-A1 SULFOXIMINE SUBSTITUTED QUINAZOLINES FOR PHARMACEUTICAL COMPOSITIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-01-01 US disclosed
US-8198458-B2 Non-nucleoside reverse transcriptase inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-06-12 US disclosed
US-7531539-B2 Pyrrolotriazine kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2009-05-12 US disclosed
US-7531539-B2 Pyrrolotriazine kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2009-05-12 US disclosed
US-7517998-B2 Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus BOEHRINGER INGELHEIM INTERNATIONAL GMBH 2009-04-14 US disclosed
US-7517998-B2 Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus BOEHRINGER INGELHEIM INTERNATIONAL GMBH 2009-04-14 US disclosed
US-20080045496-A1 PYRROLOTRIAZINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2008-02-21 US disclosed
US-20080045496-A1 PYRROLOTRIAZINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2008-02-21 US disclosed
US-7179907-B2 Antibiotic compounds SOMALOGIC OPERATING CO. INC. 2007-02-20 US disclosed
US-7179907-B2 Antibiotic compounds SOMALOGIC OPERATING CO. INC. 2007-02-20 US disclosed