Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560635 | 0.86 | KDM4E (0.66) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8461552 | 0.83 | KDM4E (0.89) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL11810869 | 0.83 | KDM4E (0.75) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL7560673 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL4948373 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL7560634 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL1145072 | 0.82 | KDM4E (0.93) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8132 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL34463427 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL11271721 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163372-A4 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1163372-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | Princeton Separations (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056933-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2000-09-28 | — | — | WO | disclosed |