Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 5/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457491 | 1.00 | DPP8 (0.32) | DPP8DPP9CCR5MMP2MMP9 | |
| SCHEMBL8105057 | 1.00 | DPP8 (0.32) | DPP8DPP9CCR5MMP2MMP9 | |
| SCHEMBL7451816 | 0.95 | DPP8 (0.32) | DPP8DPP9CCR5MMP2MMP9 | |
| SCHEMBL7458137 | 0.95 | DPP8 (0.32) | DPP8DPP9CCR5MMP2MMP9 | |
| SCHEMBL7559273 | 0.87 | GAA (0.33) | MMP2ALDH1A1MAPT | |
| SCHEMBL7458133 | 0.87 | GAA (0.33) | MMP2ALDH1A1MAPT | |
| SCHEMBL7453403 | 0.86 | CCR5 (0.32) | DPP8DPP9CCR5NPC1RAB9A | |
| SCHEMBL9574341 | 0.85 | DPP8 (0.35) | DPP8DPP9MMP2ALDH1A1MAPT | |
| SCHEMBL9574214 | 0.85 | DPP8 (0.35) | DPP8DPP9MMP2ALDH1A1MAPT | |
| SCHEMBL7460727 | 0.85 | DPP8 (0.37) | DPP8DPP9CCR5HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |