Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LGMN | Q99538 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441385 | 0.90 | KDM4E (0.40) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| Trifluoroacetic Acid SCHEMBL7447966 | 0.87 | KDM4E (0.37) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL7449755 | 0.84 | ITGB3 (0.52) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| Iodomethane SCHEMBL9367652 | 0.84 | KDM4E (0.42) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL7431827 | 0.83 | KMT2A (0.40) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL7345353 | 0.78 | ITGB3 (0.47) | SMN1; SMN2KDM4ECYP2C9CYP2C19KMT2A | |
| SCHEMBL7344483 | 0.78 | ITGB3 (0.48) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL27416769 | 0.76 | KDM4E (0.42) | GAASMN1; SMN2KDM4ECYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7341382 | 0.75 | ITGB3 (0.46) | GAAALOX12SMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL7441356 | 0.74 | ITGB3 (0.57) | KDM4ECYP2C9CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | claimed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |