SCHEMBL745010

SCHEMBL745010

CCCCCCCCCCCCCCCCN1CCNCC1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 9/20 0.65
GNAI3 P08754 8/20 0.65
GNAI1 P63096 8/20 0.65
CXCR4 P61073 2/20 0.61
SOD3 P08294 2/20 0.54
HRH2 P25021 1/20 0.46
HRH1 P35367 1/20 0.46
SIGMAR1 Q99720 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10379383 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL7336599 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL5394694 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL162842 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL744931 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL21581269 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL21581281 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL21581298 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL21581259 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3
SCHEMBL21581257 1.00 GNAO1 (0.65) GNAO1GNAI3GNAI1CXCR4SOD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-7977455-B2 Analogues of GLP-1 IPSEN PHARMA, S.A.S. (FR) 2011-07-12 US claimed
US-20090197802-A1 Analogues of GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) 2009-08-06 US claimed
EP-2067483-A1 Analogues of GLP-1 IPSEN PHARMA (FR) 2009-06-10 EP claimed
US-20080108566-A1 Analogues of GLP-1 IPSEN PHARMA S.A.S. (FR) 2008-05-08 US claimed
EP-1594529-A4 ANALOGUES OF GLP-1 SOD CONSEILS RECH APPLIC (FR) 2008-01-16 EP claimed
US-7268213-B2 Analogues of GLP-1 SOCIETE DE CONSELIS DE RECHERCHES ET D'APPLICATIONS SCIENTITIQUES, S.A.S. (FR) 2007-09-11 US claimed
CN-1935839-A Analogues of glp-1 SOD CONSEILS RECH APPLIC (FR) 2007-03-28 CN claimed
US-20060217300-A1 Analogues of glp-1 BIOMEASURE, INCORPORATED (US) 2006-09-28 US claimed
CN-1750842-A Analogues of GLP-1 SOD CONSEILS RECH APPLIC (FR) 2006-03-22 CN claimed
EP-1594529-A2 ANALOGUES OF GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2005-11-16 EP claimed
WO-2004074315-A2 ANALOGUES OF GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2004-09-02 WO claimed
CN-1495198-A Analogs of glucagon-like peptide-1 �о���Ӧ�ÿ�ѧЭ��ɷ����޹�˾ 2004-05-12 CN claimed
US-20040018981-A1 Analogues of GLP-1 BIOMEASURE INC., A MASSACHUSETTS CORPORATION 2004-01-29 US claimed
EP-1359159-A2 Analogues of GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2003-11-05 EP claimed
CN-1329620-A Glucagon-like peptide-1 analogs CONSEILS DE RECH SET D APPLIC (FR) 2002-01-02 CN claimed
EP-1137667-A2 ANALOGUES OF GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) 2001-10-04 EP claimed
WO-2000034331-A2 ANALOGUES OF GLP-1 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) 2000-06-15 WO claimed
CN-119285768-A TIGIT antibodies and uses thereof 百泰生物药业有限公司 2025-01-10 CN disclosed
EP-0076996-A1 Carboxylic-acid derivatives, process for their preparation and medicines containing them Roche Diagnostics GmbH (DE) 1983-04-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040018981-A1 Analogues of GLP-1 GLP1R, IAPP, GIPR GNAO1 1038/4885GNAI3 640/4885GNAI1 382/4885
US-20090197802-A1 Analogues of GLP-1 GLP1R, IAPP, GIPR GNAO1 1038/4885GNAI3 640/4885GNAI1 382/4885
US-20060217300-A1 Analogues of glp-1 GLP1R, IAPP, GIPR GNAO1 1010/4885GNAI3 538/4885GNAI1 317/4885
US-20080108566-A1 Analogues of GLP-1 GLP1R, IAPP, GIPR GNAO1 1038/4885GNAI3 640/4885GNAI1 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.