Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371882 | 0.82 | MAPT (0.53) | L3MBTL1RAB9ANPC1HDAC1KDM4E | |
| SCHEMBL7369711 | 0.79 | MAPT (0.62) | L3MBTL1NR4A2RAB9ANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL7368528 | 0.78 | MAPT (0.60) | L3MBTL1NR4A2RAB9ANPC1KDM4E | |
| SCHEMBL7371339 | 0.77 | KDM4E (0.47) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL5327317 | 0.77 | KDM4E (0.60) | NR4A2RAB9ANPC1KDM4EMEN1 | |
| SCHEMBL2269443 | 0.76 | HDAC3 (0.63) | NR4A2RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL2654572 | 0.75 | NR4A2 (0.56) | L3MBTL1NR4A2RXRARXRBRAB9A | |
| SCHEMBL7296687 | 0.75 | RAB9A (0.78) | NR4A2RXRARXRBRAB9ANPC1 | |
| SCHEMBL5178206 | 0.75 | RAB9A (0.69) | NR4A2RAB9ANPC1POLBCASP3 | |
| SCHEMBL7365193 | 0.74 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006535-A1 | TYROSINE-DERIVED COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |