Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.73 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138631 | 1.00 | GRIK1 (0.73) | GRIK1GRIK2HTR2AMMP13ALPI | |
| SCHEMBL7786187 | 0.85 | GRIK1 (1.00) | GRIK1GRIK2HTR2ASLC1A3SLC1A2 | |
| SCHEMBL7703039 | 0.85 | GRIK1 (1.00) | GRIK1GRIK2HTR2ASLC1A3SLC1A2 | |
| SCHEMBL7703041 | 0.85 | GRIK1 (1.00) | GRIK1GRIK2HTR2ASLC1A3SLC1A2 | |
| SCHEMBL2831614 | 0.84 | GRIK1 (0.55) | GRIK1GRIK2HTR2AMMP13ALPI | |
| SCHEMBL23139375 | 0.84 | GRIK1 (0.55) | GRIK1GRIK2HTR2AMMP13ALPI | |
| SCHEMBL24637141 | 0.84 | GRIK1 (0.55) | GRIK1GRIK2HTR2AMMP13MMP2 | |
| SCHEMBL23139425 | 0.82 | GRIK1 (0.60) | GRIK1GRIK2HTR2AALPIPKM | |
| SCHEMBL24814159 | 0.82 | GRIK1 (0.56) | GRIK1GRIK2HTR2AMMP13CYP1A2 | |
| SCHEMBL29178391 | 0.82 | GRIK1 (0.56) | GRIK1GRIK2HTR2AMMP13CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | GRIK1 2914/4885GRIK2 3197/4885HTR2A 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.