Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004822 | 0.92 | CYP1A2 (0.47) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7441787 | 0.92 | CYP1A2 (0.47) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL12526750 | 0.81 | CYP1A2 (0.49) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL17771391 | 0.81 | CYP1A2 (0.49) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL16349134 | 0.79 | CTSK (0.50) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL15244379 | 0.78 | CA1 (0.59) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL5353383 | 0.78 | CYP1A2 (0.49) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL28542468 | 0.78 | CTSK (0.42) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL25166100 | 0.77 | CYP1A2 (0.51) | CTSKCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL31059732 | 0.77 | CYP1A2 (0.51) | CTSKCYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5332726-A | Anticoagulant | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |