Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12450023 | 0.88 | NPSR1 (0.34) | NPSR1MAPTLMNAMMP1MMP2 | |
| SCHEMBL390361 | 0.81 | — | — | |
| SCHEMBL1456118 | 0.81 | NPSR1 (0.35) | NPSR1MAPTLMNAMMP2CYP4F2 | |
| SCHEMBL9550343 | 0.80 | NPSR1 (0.38) | NPSR1MAPTLMNAEPHX2CYP4F2 | |
| Hydrochloric Acid SCHEMBL3915456 | 0.79 | NPSR1 (0.34) | NPSR1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL384474 | 0.79 | NPSR1 (0.34) | NPSR1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL382967 | 0.79 | NPSR1 (0.34) | NPSR1MAPTLMNA | |
| SCHEMBL15115826 | 0.78 | FFAR3 (0.37) | NPSR1MAPTLMNAEPHX2CYP4F2 | |
| SCHEMBL3883900 | 0.78 | FFAR3 (0.37) | NPSR1MAPTLMNAEPHX2CYP4F2 | |
| SCHEMBL9041790 | 0.78 | FFAR3 (0.37) | NPSR1MAPTLMNAEPHX2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641306-A1 | CARBOCYCLIC AND HETEROCYCLIC HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1992021647-A1 | CARBOCYCLIC AND HETEROCYCLIC HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-10 | — | — | WO | claimed |
| CN-111285875-B | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111285875-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| WO-2020114474-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 苏州信诺维医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |
| WO-2020114474-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 苏州信诺维医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |