Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450755 | 1.00 | ITGB3 (0.69) | ITGB3ITGA2BOPRM1OPRD1OPRK1 | |
| SCHEMBL7440009 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BOPRM1OPRD1OPRK1 | |
| SCHEMBL7440013 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BOPRM1OPRD1OPRK1 | |
| SCHEMBL7437403 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7437406 | 0.82 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7437422 | 0.80 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL7395607 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL7395612 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677549 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677554 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |