Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 4/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423196 | 0.94 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL4190246 | 0.88 | MAPK9 (0.49) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2420532 | 0.88 | MAPK9 (0.58) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2423150 | 0.86 | MAPK9 (0.58) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2426630 | 0.85 | MEN1 (0.49) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2421952 | 0.83 | KMT2A (0.45) | MEN1KMT2AMAPK1GAAMAPT | |
| SCHEMBL3479980 | 0.82 | MEN1 (0.48) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2423342 | 0.81 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL4969141 | 0.81 | MAPK9 (0.52) | MAPK9MAPK10MEN1KMT2AMAPK1 | |
| SCHEMBL2422247 | 0.81 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |