Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455629 | 0.99 | MAPT (0.50) | MAPTTDP1L3MBTL1MAPK1HTT | |
| SCHEMBL7451566 | 0.84 | HTT (0.58) | MAPK1HTTCA1CA2CA7 | |
| SCHEMBL7451964 | 0.81 | HTT (0.48) | TDP1MAPK1HTTCA1CA2 | |
| SCHEMBL7508403 | 0.81 | HTT (0.42) | MAPTTDP1L3MBTL1HTTHTR1A | |
| SCHEMBL7976000 | 0.81 | HTT (0.50) | HTTCYP2C19KMT2AGAA | |
| SCHEMBL7450571 | 0.79 | HTT (0.53) | MAPK1HTTCA1CA2CA7 | |
| SCHEMBL7508484 | 0.79 | HTT (0.40) | HTTHTR1AMEN1KMT2A | |
| SCHEMBL7448869 | 0.76 | HTT (0.50) | MAPK1HTTCA1CA2CA7 | |
| SCHEMBL7451582 | 0.76 | HTT (0.41) | HTTMEN1KMT2A | |
| SCHEMBL7447542 | 0.75 | HTT (0.45) | HTTCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |