Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632907 | 0.88 | RAB9A (0.77) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL7299163 | 0.88 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10674350 | 0.85 | RAB9A (0.82) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL8298007 | 0.83 | RAB9A (0.79) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL15031615 | 0.83 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL1999435 | 0.83 | RAB9A (0.90) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL3626811 | 0.82 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL24658769 | 0.82 | RAB9A (0.77) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL5631833 | 0.82 | RAB9A (0.77) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL10050510 | 0.82 | RAB9A (0.85) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724578-A1 | AMINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011240-A1 | AMINE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |