SCHEMBL7451985

SCHEMBL7451985

CCCC[C@@H]1C[C@@H](NC(=O)C2(CC(CCC)C(=O)OC(C)(C)C)CCCC2)CC[C@H]1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MME P08473 18/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7513523 1.00 MME (0.52) MME
SCHEMBL7513527 1.00 MME (0.52) MME
SCHEMBL7450025 0.92 MME (0.55) MME
SCHEMBL9469621 0.82 MME (0.56) MME
SCHEMBL6429120 0.81 MME (0.73) MME
SCHEMBL9470506 0.75 MME (0.53) MME
SCHEMBL9470512 0.75 MME (0.53) MME
SCHEMBL7446884 0.75 MME (0.45) MME
SCHEMBL8334966 0.74 MME (0.49) MME
SCHEMBL8328582 0.74 MME (0.49) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020052370-A1 Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase PFIZER, INC. 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052370-A1 Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase ENGASE, ENPEP, CPN1 MME 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.