SCHEMBL7452161

SCHEMBL7452161

[N-]=[N+]=C1CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)NC1=O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 8/20 0.49
▸ PYGM P11217 3/20 0.40
▸ SLC28A1 O00337 1/20 0.40
▸ SLC28A2 O43868 1/20 0.40
▸ SLC29A1 Q99808 1/20 0.40
▸ SLC28A3 Q9HAS3 1/20 0.40
▸ MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7452167 1.00 CDA (0.49) CDAPYGMSLC28A1SLC28A2SLC29A1
SCHEMBL29047907 0.82 CDA (0.55) CDAPYGMSLC28A1SLC28A2SLC29A1
SCHEMBL10859054 0.80 CDA (0.52) CDAPYGMSLC28A1SLC28A2SLC29A1
SCHEMBL7705298 0.80 CDA (0.54) CDAPYGMSLC28A1SLC28A2SLC29A1
SCHEMBL7148871 0.79 TK1 (0.41) —
SCHEMBL2586028 0.79 — —
SCHEMBL7148864 0.79 TK1 (0.41) —
SCHEMBL2586033 0.79 — —
SCHEMBL6130423 0.73 CDA (0.53) CDAPYGMSLC28A1SLC28A2SLC29A1
SCHEMBL399314 0.72 CDA (0.66) CDAPYGMSLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0925502-A4 DIAGNOSTIC AND THERAPEUTIC NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, AND USE THEREOF UNIV KENTUCKY RES FOUND (US) 2002-12-18 — — EP disclosed
EP-0749439-A4 NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, METHODS FOR THEIR MANUFACTURE AND USE THEREOF UNIV KENTUCKY RES FOUND (US) 1999-11-03 — — EP disclosed
EP-0925502-A1 DIAGNOSTIC AND THERAPEUTIC NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, AND USE THEREOF University of Kentucky Research Foundation (US) 1999-06-30 — — EP disclosed
US-5800991-A Nucleotide or nucleoside photoaffinity compound modified antibodies, methods for their manufacture and use thereof as diagnostics and therapeutics UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1998-09-01 — — US disclosed
WO-1998003870-A9 DIAGNOSTIC AND THERAPEUTIC NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, AND USE THEREOF — 1998-05-28 — — WO disclosed
EP-0728216-A4 DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD UNIV KENTUCKY RES FOUND (US) 1998-04-29 — — EP disclosed
WO-1998003870-A1 DIAGNOSTIC AND THERAPEUTIC NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, AND USE THEREOF UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1998-01-29 — — WO disclosed
US-5693764-A Nucleotide or nucleoside photoaffinity compound modified antibodies, methods for their manufacture and use thereof as diagnostics and therapeutics THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1997-12-02 — — US disclosed
US-5596081-A Nucleotide or nucleoside photoaffinity compound modified antibodies, methods for their manufacture and use thereof as diagnostics and therapeutics UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1997-01-21 — — US disclosed
EP-0749439-A1 NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, METHODS FOR THEIR MANUFACTURE AND USE THEREOF University of Kentucky Research Foundation (US) 1996-12-27 — — EP disclosed
EP-0728216-A1 DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1996-08-28 — — EP disclosed
WO-1995024417-A1 NUCLEOTIDE OR NUCLEOSIDE PHOTOAFFINITY COMPOUND MODIFIED ANTIBODIES, METHODS FOR THEIR MANUFACTURE AND USE THEREOF THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1995-09-14 — — WO disclosed
US-5445937-A Detection of Alzheimer's disease and other diseases using an improved photoaffinity labeling method THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1995-08-29 — — US disclosed
WO-1995011314-A1 DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING AN IMPROVED PHOTOAFFINITY LABELING METHOD THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1995-04-27 — — WO disclosed
EP-0646243-A1 DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING A PHOTOAFFINITY LABELING METHOD UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1995-04-05 — — EP disclosed
US-5272055-A Detection of Alzheimer's disease and other diseases using a photoaffinity labeling method THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1993-12-21 — — US disclosed
WO-1993012755-A2 DETECTION OF ALZHEIMER'S DISEASE AND OTHER DISEASES USING A PHOTOAFFINITY LABELING METHOD THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1993-07-08 — — WO disclosed
US-4092305-A ANTIBACTERIAL, FUNGICIDES, ANTICANCER AGENTS UNIVERSITY OF UTAH RESEARCH FONDATION, (FOUNDATION) 1978-05-30 — — US disclosed
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