Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463246 | 0.87 | PPARG (0.58) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL4365146 | 0.87 | PPARG (0.58) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL7454849 | 0.85 | PPARG (0.57) | PPARGFFAR1HRH3 | |
| SCHEMBL7453517 | 0.81 | NPC1 (0.62) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL1072226 | 0.77 | FFAR1 (0.77) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL7459750 | 0.76 | MAOA (0.56) | HRH3 | |
| SCHEMBL7463022 | 0.76 | MAOA (0.56) | HRH3 | |
| SCHEMBL7462306 | 0.76 | PPARG (0.65) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL8139507 | 0.76 | FFAR1 (0.52) | PPARGFFAR1HRH3PPARA | |
| SCHEMBL5935692 | 0.76 | PPARG (0.69) | PPARGFFAR1HRH3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971917-B1 | THIAZOLIDINEDIONE AND OXAZOLIDINEDIONE DERIVATIVES HAVING ANTIDIABETIC, HYPOLIPIDAEMIC AND ANTIHYPERTENSIVE PROPERTIES | REDDY RESEARCH FOUNDATION (IN) | 2002-02-06 | — | — | EP | claimed |
| EP-0971917-B1 | THIAZOLIDINEDIONE AND OXAZOLIDINEDIONE DERIVATIVES HAVING ANTIDIABETIC, HYPOLIPIDAEMIC AND ANTIHYPERTENSIVE PROPERTIES | REDDY RESEARCH FOUNDATION (IN) | 2002-02-06 | — | — | EP | disclosed |
| US-6011036-A | Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-01-04 | — | — | US | disclosed |