Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806508 | 1.00 | LMNA (0.57) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL6368998 | 0.94 | ALPI (0.61) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL14095415 | 0.92 | ALPI (0.59) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL19167232 | 0.92 | ALPI (0.59) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL15590174 | 0.92 | ALPI (0.59) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL26231121 | 0.92 | ALPI (0.59) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL14095409 | 0.90 | ALPI (0.61) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL15679078 | 0.90 | ALPI (0.66) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL26359430 | 0.90 | ALPI (0.66) | LMNAALPIPKMPTGS1XIAP | |
| SCHEMBL23542514 | 0.89 | ALPI (0.59) | LMNAALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2641605-B1 | POLYMER DERIVATIVE OF CYTIDINE METABOLISM ANTAGONIST | NIPPON KAYAKU KK (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9018323-B2 | Polymer derivative of cytidine metabolic antagonist | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20130331517-A1 | Novel Polymer Derivative Of Cytidine Metabolic Antagonist | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-12-12 | — | — | US | disclosed |
| EP-2641605-A1 | NOVEL POLYMER DERIVATIVE OF CYTIDINE METABOLISM ANTAGONIST | Nippon Kayaku Kabushiki Kaisha (JP) | 2013-09-25 | — | — | EP | disclosed |
| EP-2431403-A1 | POLYMER CONJUGATE OF BIOACTIVE SUBSTANCE HAVING HYDROXY GROUP | Nippon Kayaku Kabushiki Kaisha (JP) | 2012-03-21 | — | — | EP | disclosed |