Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758672 | 0.89 | SLC1A3 (0.46) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Diethylamine SCHEMBL27889843 | 0.87 | RNPEP (0.39) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2412183 | 0.86 | RNPEP (0.55) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30018397 | 0.84 | SLC1A3 (0.43) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17283387 | 0.83 | SLC7A5 (0.48) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8871238 | 0.83 | SLC7A5 (0.48) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL664075 | 0.83 | SLC7A5 (0.48) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL666505 | 0.83 | SLC7A5 (0.48) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3872939 | 0.83 | SLC7A5 (0.48) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3755208 | 0.82 | NAALAD2 (0.45) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455531-B1 | METALLOPROTEINASE INHIBITORS | DARWIN DISCOVERY, LTD. (GB) | 2002-09-24 | — | — | US | disclosed |
| EP-1237868-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | Darwin Discovery Limited (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044189-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |