Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872939 | 1.00 | SLC7A5 (0.48) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL664075 | 1.00 | SLC7A5 (0.48) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8871238 | 1.00 | SLC7A5 (0.48) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7453161 | 0.83 | RNPEP (0.48) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17283387 | 0.82 | SLC7A5 (0.48) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3686597 | 0.78 | SLC1A3 (0.43) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15980616 | 0.78 | SLC1A3 (0.43) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15980617 | 0.78 | SLC1A3 (0.43) | SLC7A5RNPEPSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8872304 | 0.77 | MMP1 (0.51) | ANPEP | |
| SCHEMBL8872299 | 0.77 | MMP1 (0.51) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944248-A | Anti-aging plastic particle and preparation method thereof | 界首市鸿鑫塑业有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-104290364-B | Plastic wire of a kind of anti-light aging and preparation method thereof | NINGXIA RUNLONG PACKAGING NEW MATERIAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-105175276-A | Synthetic method for optically pure(R)-3-carbamyl methyl-5-methyl caproic acid | EASTSKY PHARM ANHUI TECHNOLOGY CO LTD | 2015-12-23 | — | — | CN | claimed |
| CN-104290364-A | Anti-photoaging plastic filament and preparation method of anti-photoaging plastic filament | NINGXIA RUNLONG PACKAGING NEW MATERIAL CO LTD | 2015-01-21 | — | — | CN | claimed |
| US-20140323758-A1 | NOVEL PROCESS FOR RACEMIZATION OF AN OPTICALLY ACTIVE (S)-3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID TO CORRESPONDING 3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID RACEMATE | LUPIN LIMITED (IN) | 2014-10-30 | — | — | US | claimed |
| EP-2782901-A1 | NOVEL PROCESS FOR RACEMIZATION OF AN OPTICALLY ACTIVE (S)-3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID TO CORRESPONDING 3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID RACEMATE | Lupin Limited (IN) | 2014-10-01 | — | — | EP | claimed |
| WO-2013076630-A1 | NOVEL PROCESS FOR RACEMIZATION OF AN OPTICALLY ACTIVE (S)-3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID TO CORRESPONDING 3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID RACEMATE | LUPIN LIMITED (IN) | 2013-05-30 | — | — | WO | claimed |
| US-20090137842-A1 | PREGABALIN -4-ELIMINATE, PREGABALIN 5-ELIMINATE, THEIR USE AS REFERENCE MARKER AND STANDARD, AND METHOD TO PRODUCE PREGABALIN CONTAINING LOW LEVELS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-28 | — | — | US | claimed |
| WO-2009046309-A2 | PREGABALIN -4-ELIMINATE, PREGABALIN 5-ELIMINATE, THEIR USE AS REFERENCE MARKER AND STANDARD, AND METHOD TO PRODUCE PREGABALIN CONTAINING LOW LEVELS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-04-09 | — | — | WO | claimed |
| CN-111944248-A | Anti-aging plastic particle and preparation method thereof | 界首市鸿鑫塑业有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-209655725-U | A kind of total closed type bipyramid drying device | JIANGXI JINFENG PHARMACEUTICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-209655725-U | A kind of total closed type bipyramid drying device | JIANGXI JINFENG PHARMACEUTICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-104290364-B | Plastic wire of a kind of anti-light aging and preparation method thereof | NINGXIA RUNLONG PACKAGING NEW MATERIAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | disclosed |
| EP-2391600-B1 | INTERMEDIATES IN THE ENANTIOSELECTIVE SYNTHESIS OF 3-(AMINOMETHYL)-5-METHYL-HEXANOIC ACID | PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2016-01-06 | — | — | EP | disclosed |
| US-20070287859-A1 | Optical resolution of 3-carbamoylmethyl-5-methyl hexanoic acid | HEDVATI LILACH | 2007-12-13 | — | — | US | disclosed |
| US-20070191636-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | TEVA PHARMACEUTICAL USA, INC. | 2007-08-16 | — | — | US | disclosed |
| US-5703092-A | TREATING ARTHRITIS, OTHER INFLAMMATORY DISEASES MEDIATED BY MATRIX METALLOPROTEINASE AND/OR TUMOR NECROSIS FACTOR | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0684830-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0684830-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994017817-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137842-A1 | PREGABALIN -4-ELIMINATE, PREGABALIN 5-ELIMINATE, THEIR USE AS REFERENCE MARKER AND STANDARD, AND METHOD TO PRODUCE PREGABALIN CONTAINING LOW LEVELS THEREOF | GABRG2, GABRG1, GABRA5 | SLC7A5 748/4885RNPEP 846/4885SLC1A3 368/4885 |
| US-20140323758-A1 | NOVEL PROCESS FOR RACEMIZATION OF AN OPTICALLY ACTIVE (S)-3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID TO CORRESPONDING 3-CARBAMOYLMETHYL-5-METHYL-HEXANOIC ACID RACEMATE | ACMSD, HCAR3, ALKBH5 | SLC7A5 1952/4885RNPEP 957/4885SLC1A3 1345/4885 |
| US-20070287859-A1 | Optical resolution of 3-carbamoylmethyl-5-methyl hexanoic acid | GRM3, GRM6, GABRE | SLC7A5 1934/4885RNPEP 3151/4885SLC1A3 214/4885 |
| US-20070191636-A1 | Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin | GABRE, GABRA5, GABRA6 | SLC7A5 819/4885RNPEP 3729/4885SLC1A3 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.