SCHEMBL7453273

SCHEMBL7453273

NC(=O)C1CCN(Cc2csc3c(OC(=O)C(F)(F)F)nccc23)C1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7453196 0.86 F2 (0.30)
Trifluoroacetic Acid SCHEMBL7213615 0.84 L3MBTL1 (0.32) MET
Trifluoroacetic Acid SCHEMBL7457541 0.84 F10 (0.33) MET
Trifluoroacetic Acid SCHEMBL7215785 0.84 F10 (0.33) MET
SCHEMBL7448311 0.81 F10 (0.40) MET
SCHEMBL7214400 0.81 F10 (0.40) MET
Trifluoroacetic Acid SCHEMBL7446696 0.73 KDR (0.35)
Trifluoroacetic Acid SCHEMBL7219407 0.73 KDR (0.35)
Trifluoroacetic Acid SCHEMBL7219132 0.73 KDR (0.35)
Trifluoroacetic Acid SCHEMBL7219220 0.73 F2 (0.34) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001039759-A2 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-06-07 WO disclosed