SCHEMBL745348

SCHEMBL745348

C=C(CCC(=O)OCC)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
GAA P10253 2/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALDH1A1 P00352 6/20 0.43
TRPA1 O75762 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 3/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 2/20 0.41
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
NR1I2 O75469 1/20 0.38
PGR P06401 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
PTGS2 P35354 1/20 0.38
PDE4D Q08499 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B10 Q99714 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699623 0.88 CYP1A2 (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL4869440 0.83 CYP1A2 (0.47) CYP1A2GAAMGAMSIMGAM2
Succinic Acid Diethyl Ester SCHEMBL27768067 0.81 GAA (0.67) CYP1A2GAAMGAMSIMGAM2
Succinic Acid Diethyl Ester SCHEMBL22780 0.81 GAA (0.67) CYP1A2GAAMGAMSIMGAM2
SCHEMBL262251 0.80 GAA (0.61) CYP1A2GAAMGAMSIMGAM2
SCHEMBL6178625 0.79 GAA (0.52) CYP1A2GAAMGAMSIMGAM2
Hydrochloric Acid SCHEMBL8773043 0.79 CYP1A2 (0.48) CYP1A2GAAMGAMSIMGAM2
Succinic Acid Diethyl Ester SCHEMBL28197993 0.79 GAA (0.57) CYP1A2GAAMGAMSIMGAM2
SCHEMBL6551275 0.78 GAA (0.58) CYP1A2GAAMGAMSIMGAM2
SCHEMBL11694427 0.78 GAA (0.58) CYP1A2GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338937-A1 Supported Hydrotreating Catalysts Having Enhanced Activity KETJEN NETHERLANDS B.V. (NL) 2023-10-26 US disclosed
US-11731118-B2 Supported hydrotreating catalysts having enhanced activity Albemarle Catalysts Company B.V. (NL) 2023-08-22 US disclosed
WO-2023079070-A1 SUPPORTED HYDROTREATING CATALYSTS HAVING ENHANCED ACTIVITY Albemarle Catalysts Company B.V. (NL) 2023-05-11 WO disclosed
EP-2906344-B1 SUPPORTED HYDROTREATING CATALYSTS HAVING ENHANCED ACTIVITY ALBEMARLE EUROPE SPRL (BE) 2022-12-07 EP disclosed
US-20220055026-A1 Supported Hydrotreating Catalysts Having Enhanced Activity KETJEN NETHERLANDS B.V. (NL) 2022-02-24 US disclosed
US-20210399288-A1 PARTICLES COMPRISING SILICON AND LITHIUM ALBEMARLE CORPORATION 2021-12-23 US disclosed
EP-3864717-A1 PARTICLES COMPRISING SILICON AND LITHIUM ALBEMARLE CORPORATION (US) 2021-08-18 EP disclosed
US-20210189182-A1 ADHESIVE FILM AND LAMINATE FILM INCLUDING THE SAME INNOX ADVANCED MATERIALS CO., LTD. (KR) 2021-06-24 US disclosed
EP-3721292-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE Covestro Deutschland AG (DE) 2020-10-14 EP disclosed
EP-3710415-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed
CN-1143323-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORP (US) 1997-02-19 CN disclosed
US-5235059-A Topically treating ocular hypertension and glaucoma MERCK & CO., INC. (US) 1993-08-10 US disclosed
EP-0093924-B1 PHOTOGRAPHIC REGISTRATION MATERIAL Agfa-Gevaert AG (DE) 1987-05-27 EP disclosed
US-4513080-A BASED ON A CARBOXYLIC AMIDE AGFA-GEVAERT AG (DE) 1985-04-23 US disclosed
EP-0093924-A2 Photographic registration material Agfa-Gevaert AG (DE) 1983-11-16 EP disclosed
US-4198517-A Histidine derivatives E. R. SQUIBB & SONS, INC. (US) 1980-04-15 US disclosed
US-4154736-A Indolylalkylene amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4128721-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4127729-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-11-28 US disclosed
US-4091024-A Pyrrolidine and piperidine-2-carboxylic acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-05-23 US disclosed