Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452186 | 0.90 | APEX1 (0.53) | APEX1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7452329 | 0.87 | APEX1 (0.59) | APEX1MEN1KMT2APKMTP53 | |
| SCHEMBL13870858 | 0.80 | MEN1 (0.82) | APEX1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL7449698 | 0.79 | APEX1 (0.66) | APEX1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL7452639 | 0.79 | RXFP1 (0.55) | APEX1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL7446031 | 0.77 | APEX1 (0.71) | APEX1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL7453890 | 0.76 | MEN1 (0.70) | APEX1MEN1KMT2APKMLMNA | |
| SCHEMBL7449361 | 0.76 | MEN1 (0.72) | APEX1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL7826133 | 0.75 | APEX1 (0.66) | APEX1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL4094983 | 0.75 | MEN1 (0.66) | MEN1KMT2APKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |