Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.50 |
| ▸ | PLAU | P00749 | 6/20 | 0.50 |
| ▸ | PLG | P00747 | 3/20 | 0.50 |
| ▸ | KLK1 | P06870 | 3/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 2/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438444 | 0.85 | PRSS1 (0.63) | F2PRSS1PLAUPLGTMPRSS2 | |
| SCHEMBL7336793 | 0.78 | PTPN7 (0.61) | F2PRSS1PLAUPLGKLK1 | |
| SCHEMBL19430950 | 0.76 | PRSS1 (0.59) | F2PRSS1PLAUPLGTMPRSS2 | |
| SCHEMBL19430435 | 0.75 | F2 (0.52) | F2PRSS1PLAUPLGKLK1 | |
| SCHEMBL7344446 | 0.75 | PLAU (0.54) | F2PRSS1PLAUPLGKLK1 | |
| SCHEMBL2121782 | 0.74 | AGXT (0.57) | ALDH1A1LMNAMAPT | |
| SCHEMBL19479048 | 0.74 | PRSS1 (0.60) | F2PRSS1PLAUPLGTMPRSS2 | |
| SCHEMBL19430636 | 0.74 | F2 (0.74) | F2PRSS1PLAUF10ST14 | |
| SCHEMBL7346756 | 0.74 | PRSS1 (0.55) | F2PRSS1PLAUPLGTMPRSS2 | |
| SCHEMBL8310667 | 0.74 | PLAU (0.58) | F2PRSS1PLAUPLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975608-A2 | HALO-ALKOXYCARBONYL PRODRUGS | Genentech, Inc. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046576-A2 | HALO-ALKOXYCARBONYL PRODRUGS | GENENTECH, INC. (US) | 1998-10-22 | — | — | WO | disclosed |