Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 19/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 18/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7229468 | 0.97 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7229470 | 0.91 | ADORA3 (0.47) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7229473 | 0.90 | ADORA3 (0.47) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5086052 | 0.87 | ADORA3 (0.68) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7455750 | 0.85 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7520311 | 0.83 | ADORA2A (0.76) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7463149 | 0.83 | ADORA2A (0.76) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7520314 | 0.83 | ADORA2A (0.76) | ADORA3ADORA2AADORA2BADORA1 | |
| Trifluoroacetic Acid SCHEMBL7229816 | 0.83 | ADORA3 (0.67) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5088768 | 0.82 | ADORA2A (0.60) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | claimed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | claimed |