Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461911 | 0.74 | — | — | |
| SCHEMBL27895194 | 0.74 | TSHR (0.48) | TSHRCYP1A2MAPK1 | |
| SCHEMBL7743643 | 0.74 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL27294287 | 0.74 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL8191870 | 0.74 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL21984774 | 0.72 | TSHR (0.41) | TSHRCYP1A2MAPK1 | |
| SCHEMBL8883207 | 0.72 | TSHR (0.31) | TSHRCYP1A2MAPK1 | |
| SCHEMBL153525 | 0.70 | TSHR (0.30) | TSHR | |
| SCHEMBL11668780 | 0.70 | TSHR (0.33) | TSHRCYP1A2MAPK1 | |
| SCHEMBL149548 | 0.69 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216256-B | A kind of synthetic method of N, N- diisopropyl ethylenediamine | 舞阳威森生物医药有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-107216256-A | A kind of synthetic method of N, N diisopropyl ethylenediamine | 江苏斯威森生物医药工程研究中心有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-107216256-B | A kind of synthetic method of N, N- diisopropyl ethylenediamine | 舞阳威森生物医药有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-107216256-A | A kind of synthetic method of N, N diisopropyl ethylenediamine | 江苏斯威森生物医药工程研究中心有限公司 | 2017-09-29 | — | — | CN | disclosed |
| US-6204384-B1 | THROMBIN INHIBITOR; ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6011047-A | Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors | CORVAS INTERNATIONAL INC. (US) | 2000-01-04 | — | — | US | disclosed |
| WO-1999026920-A1 | SUBSTITUTED 3-AMINO-2-HYDROXYPHENYLACETAMIDE DERIVATIVES AS ENZYME INHIBITORS (II) | CORVAS INTERNATIONAL, INC. (US) | 1999-06-03 | — | — | WO | disclosed |