Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454401 | 0.74 | TSHR (0.35) | TSHRCYP1A2MAPK1 | |
| SCHEMBL8191870 | 0.70 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL27294287 | 0.70 | TSHR (0.32) | TSHRCYP1A2MAPK1 | |
| SCHEMBL6751655 | 0.69 | — | — | |
| SCHEMBL7906814 | 0.69 | — | — | |
| SCHEMBL8883207 | 0.68 | TSHR (0.31) | TSHRCYP1A2MAPK1 | |
| SCHEMBL5244719 | 0.67 | TSHR (0.30) | TSHR | |
| SCHEMBL153525 | 0.67 | TSHR (0.30) | TSHR | |
| SCHEMBL28630073 | 0.66 | — | — | |
| SCHEMBL7191400 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109825-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS INC (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-1109825-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS, INC. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012563-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999010365-A2 | 5',5'-LINKED OLIGOMERS HAVING ANTI-THROMBIN ACTIVITY | GILEAD SCIENCES, INC. (US) | 1999-03-04 | — | — | WO | disclosed |