Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.77 |
| ▸ | HTR2B | P41595 | 8/20 | 0.77 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.50 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7660022 | 0.99 | HTR2C (0.75) | HTR2CHTR2BHPSEKDM4EMAPT | |
| SCHEMBL7375771 | 0.90 | HTR2C (0.81) | HTR2CHTR2BKDM4EMAPTIGF1R | |
| SCHEMBL7369676 | 0.88 | HTR2C (0.78) | HTR2CHTR2BKDM4EMAPTIGF1R | |
| Hydrochloric Acid SCHEMBL7655770 | 0.87 | HTR2C (0.77) | HTR2CHTR2BIGF1RKDRPDGFRA | |
| Hydrochloric Acid SCHEMBL7664592 | 0.86 | HTR2C (0.98) | HTR2CHTR2BKDM4EMAPTIGF1R | |
| Hydrochloric Acid SCHEMBL7652249 | 0.86 | HTR2C (0.75) | HTR2CHTR2BIGF1RKDRPDGFRA | |
| Hydrochloric Acid SCHEMBL7376632 | 0.85 | HTR2C (0.74) | HTR2CHTR2BKDM4EMAPTIGF1R | |
| Hydrochloric Acid SCHEMBL7373000 | 0.85 | HTR2C (0.74) | HTR2CHTR2BKDM4EMAPTIGF1R | |
| Hydrochloric Acid SCHEMBL7657753 | 0.83 | HTR2C (0.71) | HTR2CHTR2BIGF1RKDRGSK3A | |
| Hydrochloric Acid SCHEMBL7654812 | 0.81 | HTR2C (0.67) | HTR2CHTR2BKDM4EMAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003737-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009024-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-25 | — | — | WO | disclosed |