Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 10/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947451 | 0.80 | MEN1 (0.75) | MEN1KMT2ATDP1SLC6A9KAT6A | |
| SCHEMBL7806590 | 0.78 | MEN1 (0.44) | MEN1KMT2ATDP1PDE4BKCNH2 | |
| SCHEMBL6944499 | 0.78 | MEN1 (0.62) | MEN1KMT2ATDP1SLC6A9PDE4B | |
| SCHEMBL6944968 | 0.78 | MAP2K1 (0.61) | MEN1KMT2ATDP1 | |
| SCHEMBL1078849 | 0.76 | MAP2K1 (0.62) | MEN1KMT2ATDP1PDE4B | |
| SCHEMBL7784128 | 0.74 | MEN1 (0.45) | MEN1KMT2ATDP1 | |
| SCHEMBL20155682 | 0.71 | BRD4 (0.59) | SLC6A9BRD4 | |
| SCHEMBL6948716 | 0.70 | AURKA (0.51) | MEN1KMT2ATDP1PDE4B | |
| SCHEMBL6947424 | 0.70 | MEN1 (0.63) | MEN1KMT2ATDP1PDE4B | |
| SCHEMBL7848269 | 0.69 | MEN1 (0.48) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202724-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005393-A2 | METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |