Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADH5 | P11766 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945667 | 0.80 | MAP2K1 (0.56) | MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL7454752 | 0.78 | MEN1 (0.48) | MEN1KMT2ATDP1PDE4BKCNH2 | |
| SCHEMBL6952545 | 0.76 | MAP2K1 (0.50) | MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL6948718 | 0.72 | MAP2K1 (0.48) | MEN1KMT2ATNIKMAPTADH5 | |
| SCHEMBL7784128 | 0.72 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1IRAK4 | |
| SCHEMBL1078849 | 0.72 | MAP2K1 (0.62) | MEN1KMT2ATDP1PDE4APDE4B | |
| SCHEMBL6952054 | 0.71 | TNIK (0.42) | TNIKMAPTADH5PDE4APDE4B | |
| SCHEMBL7848269 | 0.65 | MEN1 (0.48) | MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL7743110 | 0.65 | MEN1 (0.48) | MEN1KMT2ATDP1MAP2K1 | |
| SCHEMBL7745819 | 0.65 | MEN1 (0.53) | MEN1KMT2ATDP1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150950-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000041505-A2 | ANTHRANILIC ACID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |