Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 7/20 | 0.42 |
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433471 | 1.00 | NR1H2 (0.47) | NR1H2NR1H3LMNACNR1CNR2 | |
| SCHEMBL12363309 | 0.92 | NR1H2 (0.54) | NR1H2NR1H3LMNACNR1CNR2 | |
| SCHEMBL18717595 | 0.86 | NR1H2 (0.59) | NR1H2NR1H3CNR1CNR2KCNH2 | |
| SCHEMBL16671999 | 0.82 | NR1H2 (0.49) | NR1H2NR1H3CNR1CNR2CYP1A2 | |
| SCHEMBL25405556 | 0.82 | LMNA (0.43) | NR1H2NR1H3LMNACNR1MGLL | |
| SCHEMBL17124988 | 0.81 | NR1H2 (0.63) | NR1H2NR1H3CNR1CNR2 | |
| SCHEMBL1782896 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3CNR1CNR2KCNH2 | |
| SCHEMBL23794973 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3CNR1CNR2KCNH2 | |
| SCHEMBL12619325 | 0.81 | NR1H2 (0.47) | NR1H2NR1H3LMNACNR1CNR2 | |
| SCHEMBL20482223 | 0.80 | NR1H2 (0.46) | NR1H2NR1H3CNR1CNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368732-B1 | POLYARYLENEVINYLIENE POLYER | SAMSUNG SDI CO., LTD. (KR) | 2002-04-09 | — | — | US | disclosed |