SCHEMBL7455264

SCHEMBL7455264

BrCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.68
DRD2 P14416 2/20 0.48
DRD4 P21917 2/20 0.48
DRD3 P35462 2/20 0.48
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
MAOA P21397 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5355390 0.85 PNMT (0.64) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7195192 0.84 PNMT (0.72) PNMTDRD2DRD4DRD3NPC1
SCHEMBL5366733 0.84 PNMT (0.72) PNMTDRD2DRD4DRD3NPC1
SCHEMBL10494169 0.83 PNMT (0.47) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7603814 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7607164 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7609046 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1
SCHEMBL7606240 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1
SCHEMBL9859906 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6558685 0.82 PNMT (0.70) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578741-A OLEFIN POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-11-26 US claimed
CN-107033150-B One kind three and the trapezoidal organic semiconductor laser material of carbazyl and the preparation method and application thereof 南京邮电大学 2019-03-08 CN disclosed
CN-103864586-B Bis ether compound and resin combination with fluorene skeleton 新日铁住金化学株式会社 2018-01-09 CN disclosed
CN-107245037-A A kind of trapezoidal macromolecular derivatives and preparation method and application 南京邮电大学 2017-10-13 CN disclosed
CN-107056627-A A kind of organic semiconductor laser material and preparation method and application 南京邮电大学 2017-08-18 CN disclosed
CN-107033150-A One kind three and the trapezoidal organic semiconductor laser material of carbazyl and preparation method and application 南京邮电大学 2017-08-11 CN disclosed
CN-1368962-A Fluorene derivatives MERCK PATENT GMBH (DE) 2002-09-11 CN disclosed
US-6369254-B1 COORDINATION CATALYST FOR POLYMERIZATION CATALYSTS BASELL TECHNOLOGY COMPANY BV (NL) 2002-04-09 US disclosed
EP-0846122-B1 BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY BV (NL) 2000-07-05 EP disclosed
EP-0846122-A1 BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company B.V. (NL) 1998-06-10 EP disclosed
US-5646323-A COMPLEXING CYCLOPENTADIENYL-TYPE LIGAND, ALKALI METAL ALKYL, AND GROUP IVB OR VB METAL HALIDE TO FORM POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-07-08 US disclosed
US-5591879-A INTERMEDIATES FOR METALLOCENE POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1997-01-07 US disclosed
US-5583189-A USING A CATALYST SYSTEM COMPRISING THE REACTION PRODUCT OF A METALLOCENE COMPOUND, A SOLID ORGANOALUMINOXY PRODUCT AND AN ORGANOMETAL COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1996-12-10 US disclosed
WO-1996038458-A1 BRIDGED METALLOCENE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-12-05 WO disclosed
US-5578741-A OLEFIN POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-11-26 US disclosed
US-5565396-A METALLOCENE AND AN ORGANOALUMINOXANE COCATALYST FOR HOMO OR COPOLYMERIZING OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US disclosed
US-5563284-A COORDINATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1996-10-08 US disclosed
US-5554795-A Process for preparing cyclopentadienyl-type ligands PHILLIPS PETROLEUM COMPANY (US) 1996-09-10 US disclosed
US-5496781-A OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1996-03-05 US disclosed
EP-0683179-A1 Metallocene catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-11-22 EP disclosed