Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7450419 | 0.99 | ITGB3 (0.58) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| SCHEMBL7449397 | 0.97 | ITGB3 (0.60) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| Hydrochloric Acid SCHEMBL7451905 | 0.97 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| SCHEMBL7449994 | 0.94 | ITGB3 (0.62) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| Hydrochloric Acid SCHEMBL7446952 | 0.93 | ITGB3 (0.61) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| SCHEMBL7449818 | 0.91 | ITGB3 (0.70) | ITGB3ITGA2BALDH1A1FPR2SMN1; SMN2 | |
| SCHEMBL7450177 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| Hydrochloric Acid SCHEMBL7447965 | 0.91 | ITGB3 (0.69) | ITGB3ITGA2BALDH1A1FPR2SMN1; SMN2 | |
| SCHEMBL7444770 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 | |
| SCHEMBL7450561 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BEPHX2ALDH1A1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |