Sitafloxacin Anhydrous

Sitafloxacin Anhydrous

SCHEMBL74553

N[C@@H]1CN(c2c(F)cc3c(=O)c(C(=O)O)cn([C@@H]4C[C@@H]4F)c3c2Cl)CC12CC2

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

gyrAgyrBparCparE

The experimentally established mechanism targets of Sitafloxacin Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
POLB P06746 3/20 0.59
CHRM2 P08172 1/20 0.59
CHRM1 P11229 1/20 0.59
OPRM1 P35372 1/20 0.59
OPRD1 P41143 1/20 0.59
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 1/20 0.47
KCNH2 Q12809 4/20 0.42
AADAT Q8N5Z0 2/20 0.40
KDM4E B2RXH2 4/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
TOP2A P11388 4/20 0.39
TOP2B Q02880 4/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALB P02768 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
TUBB4A P04350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sitafloxacin Anhydrous SCHEMBL21416358 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL2784482 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL3198924 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL8509346 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL29821427 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL13483604 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL1652843 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL29368438 1.00 ALDH1A1 (0.59) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL1060786 0.99 POLB (0.58) ALDH1A1POLBCHRM2CHRM1OPRM1
Sitafloxacin Anhydrous SCHEMBL29391142 0.99 POLB (0.58) ALDH1A1POLBCHRM2CHRM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5095 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746896-A1 TREATMENT OF STAPHYLOCOCCAL ABSCESSES Katholieke Universiteit Leuven (BE) 2026-05-27 EP claimed
CN-122036535-A Antibacterial sitafloxacin preparation method of star intermediate 惠州信立泰药业有限公司 2026-05-15 CN claimed
US-12624057-B2 Bisphosphonate quinolone conjugates and uses thereof BIOVINC, LLC (US) 2026-05-12 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 EP claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4659014-A1 EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2025-12-10 EP claimed
EP-4658376-A1 SKIN CARE COMPOSITIONS Colgate-Palmolive Company (US) 2025-12-10 EP claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-1308160-A1 HIGHLY ABSORBABLE SOLID PREPARATION DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-05-07 EP claimed
EP-1305048-A2 INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES Wockhardt Limited (IN) 2003-05-02 EP claimed
WO-2003020200-A2 A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME NEW RIVER PHARMACEUTICALS INC. (US) 2003-03-13 WO claimed
US-20030045544-A1 Bactericides for the oral region of animals using 3-carboxy-4-oxo quinoline or 1,8-naphthyridine derivatives or 1-cyclopropyl-3-carboyx-4-oxo quinolizine derivatives BAYER INNOVATION GMBH (DE) 2003-03-06 US claimed
EP-1277471-A1 STABLE LIQUID PREPARATION DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-22 EP claimed
US-20020177559-A1 Quinolone derivatives WOCKHARDT LIMITED 2002-11-28 US claimed
EP-1244434-A2 USE OF CHEMOTHERAPEUTIC AGENTS Schulz, Hans-Herrmann (DE) 2002-10-02 EP claimed
WO-2002009758-A2 INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES WOCKHARDT LIMITED (IN) 2002-02-07 WO claimed
WO-2001045679-A2 USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT SCHULZ HANS HERRMANN (DE) 2001-06-28 WO claimed
EP-0643058-A1 Crystals of an antimicrobial compound DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-03-15 EP claimed